Digestive system


Digestive System

Contains probiotic spores of the following strains: Bacillus clausii, Bacillus subtilis, Bacillus coagulans.


  • Supplements probiotic spores to re-balance the intestinal microflora
  • Supports digestion, helps reducing the symptoms of colitis and symptoms of digestive disorders due to intestinal dysbiosis: Constipation, diarrhea, raw stool
  • Helps reducing the symptoms of acute diarrhea and digestive disorders
  • Helps reducing constipation, dyspepsia and flatulence
  • Stimulates digestion, improves appetizing and enhances immunology

Associated publications

Publications on effectiveness of Bacillus related to diarrhea

Tham TN, Dung P Le, Anh PB, Anh VTN, Anh HN. Improvement of Gut Microbiome by Oral Administraon of Liquid-Suspension Bacillus clausii Spores in the Rabbit Model. ASM Microbe 2022 in Washington, DC, June 9-13, 2022. 

My TT, Dung LP, Lien NT, Anh VNT, Anh NH. Stability and safety study of liquid-suspension bacillus clausii spore probiotics (Livespo Clausy). Journal of Medical Research. 2022; p. jmr 154 e10 (6).

Jayanthi N, & Sudha RM. Bacillus clausii-The probiotic of choice in the treatment of diarrhoea. Journal of Yoga & Physical Therapy, 2015; 5(4), 1

Suva MA, Sureja VP & Kheni DB. Novel insight on probiotic Bacillus subtilis: mechanism of action and clinical applications. Journal of Current Research in Scientific Medicine.2016; 2(2), 65. 

Associated publications

Publications on effectiveness of Bacillus related to colitis

Nguyen Thanh Binh, Tran Thi Nhu Quynh, Ho Thanh Thuy, Nguyen Thi Tham, Nguyen Hoa Anh. Multi – strain and high concentrated Bacillus spore probiotics support treatment of inflammatory bowel disease. Journal of Medical Research, Hanoi Medical University, 2021; 140(1), 220-228. https://tapchinghiencuuyhoc.vn/index.php/tcncyh/article/view/152 

Bamola VD, Dubey D, Samanta P, Kedia S, Madempudi RS, Neelamraju J & Chaudhry R. Effect of Bacillus coagulans Unique IS-2 in Inflammatory Bowel Disease (IBD): A Randomized Controlled Trial. medRxiv. 2021; doi: https://doi.org/10.1101/2021.07.18.21260556 

Rhayat, L., Maresca, M., Nicoletti, C., Perrier, J., Brinch, K. S., Christian, S., … & Eckhardt, E. Effect of Bacillus subtilis strains on intestinal barrier function and inflammatory response. Frontiers in immunology, 2019;10, 564. 

Selvam R, Maheswari P, Kavitha P, Ravichandran M, Sas B, Ramchand CN. Effect of Bacillus subtilis PB6, a natural probiotic on colon mucosal inflammation and plasma cytokines levels in inflammatory bowel disease. Indian Journal of Biochemistry and Biophysics. 2009. pp. 79–85

Associated publications

Publications on effectiveness of Bacillus related to constipation and anorexia

Customers’s feedbacks about LiveSpo® Pregmom


Madempudi RS, Neelamraju J, Ahire JJ, Gupta SK, Shukla VK.

Bacillus coagulans Unique IS2 in Constipation: A Double-Blind, Placebo-Controlled Study.

Probiotics and Antimicrobial Proteins. 2020. pp. 335–342. doi:10.1007/s12602-019-09542-9

Lipovec NC, Orel R.

Effect of Daily Bacillus subtilis DE111 ® Intake on Gastrointestinal Health and Respiratory Infections in Children Attending Day-care: A Randomised, Parallel, Double-blind, Placebo Eosinophilic esophagitis View project IBD cohort View project.

Artic J Probiotics Heal. 2020. Available: https://www.researchgate.net/publication/349732696

Lactulose plus live binary Bacillus subtilis in the treatment of elders with functional constipation

Liu YP, Liu X, & Dong L.

Lactulose plus live binary Bacillus subtilis in the treatment of elders with functional constipation.

Zhonghua yi xue za zhi,2012; 92(42), 2961-2964.

Associated publications

Publications on effectiveness of Bacillus related to acute diarehea

Customer’s reviews for improvement of LiveSpo® Dia30

DE C, Jo-Anne A.; GUNO, Mary JVR; PEREZ, Marcos O.

Bacillus clausii as adjunctive treatment for acute community-acquired diarrhea among Filipino children: a large-scale, multicenter, open-label study (CODDLE). 

Tropical diseases, travel medicine and vaccines, 2019; 5.1: 1-9

Ianiro G, Rizzatti G, Plomer M, Lopetuso L, Scaldaferri F, Franceschi F, et al.

Bacillus clausii for the treatment of acute diarrhea in children: a systematic review and meta-analysis of randomized controlled trials.

Nutrients. 2018;10: 1074.

Sudha MR, Bhonagiri S, & Kumar MA.

Efficacy of Bacillus clausii strain UBBC-07 in the treatment of patients suffering from acute diarrhoea.

Beneficial Microbes. 2013; 4(2), 211-216.  doi: 10.3920/BM2012.0034.

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